Serum lipoprotein (a) in diabetic patients with various renal function not yet on dialysis

To examine the association of serum serum lipoprotein(a)[lp(a)] concentration with various demographic and biochemical indexes of diabetic patients , we conducted a study on type 2 diabetes mellitus (t2d) patients. patients were under treatment with insulin injection or oral hypoglycemic agents with various creatinine clearances not yet on dialysis. we studied 122 patients, with a mean age of 63 ± 10 years .the duration of diabetes was 7.4 ± 5.8 years. in this cross-sectional study, serum lp(a), hba1c , body mass index (bmi) and creatinine clearance were assessed. the mean serum lp(a) was 22.2 ± 24.7 mg/dl (median: 18.3 mg/dl), and serum lp(a) levels more than 30 mg/dl was found in 29 (23.8%) patients. a significant inverse correlation of serum lp(a) with clearance of creatinine was observed. this study suggests that renal function is an independent determinant of serum lp(a) in diabetic patients.