Diagnostic value of ischemia-modified albumin in acute coronary syndrome and acute ischemic stroke

Objective: to investigate diagnostic value of ischemia-modified albumin (ima) levels in patients applying to emergency with symptoms of acute coronary syndrome (acs) and acute ischemic stroke (ais). methods: two patient groups (acs and ais) and a control group were constituted. the study was discontinued upon reaching 30 patients in each group. following patient approval at the initial visit, a total of 10 ml venous blood sample was obtained from all patients with a high clinical suspicion of acs and ais. the troponin i and the ima levels were determined in the blood samples. results: statistically significant higher ima values were determined in the patient groups compared to the control group (p < 0.001 for both groups). no statistically significant correlation was found between the ima and the troponin i values in the acs and the ais groups (p>0.05 for both groups). the sensitivity of ima was 83% and 87% for acs and ais, respectively. the specificity of ima was 90% and 87% for acs and ais, respectively. conclusion: the sensitivity and specificity values, determined according to the optimal cut-off values in the groups demonstrated that ima could be a useful diagnostic marker in acs and ais patients.