Stevens Johnson Syndrome associated with Lamotrigine

Stevens-johnsons syndrome (sjs) is an immune-complex-mediated hypersensitivity reaction and has been linked as an adverse side effects to many drugs. lamotrigine, an anticonvulsive medication and also a commonly used mood stabiliser, can be associated with this adverse reaction. although this has not been reported very commonly , sjs has high mortality and morbidity and requires careful attention as the use of lamotrigine is increasing in clinical practice. we present a case where the patient developed stevens - johnson syndrome three weeks after being started on lamotrigine. the case is discussed for its relevance to the use of lamotrigine which is currently prescribed very commonly in psychiatric practices.