Frequency of Vitamin D deficiency in pregnant diabetics at Baskent University Hospital, Istanbul

Objective: to find out the frequency of vitamin d deficiency and its relation with glucose parameters and the incidence of gestational diabetes (gdm). methodology: gestational diabetes was diagnosed with 75 gram oral glucose tolerance test. forty-four pregnant women diagnosed with gdm and 78 non-gdm pregnant women were enrolled as case and control group, respectively in this descriptive study. vitamin d status was classified as deficiency at ≤20 ng/ml for serum 25(oh)d concentrations. results: the mean ages were 33.4±5.2 (18-44) years and 29.7±4.1 (21-39) years, mean bmi was 30.6±5.9 kg/m² (19.5-46.1) and 25.9±4.4 kg/m2 (16.5-38) in case and control groups, respectively. the frequency of gdm was found 9.38%. the mean serum vitamin d levels in gdm group were significantly lower than in non-gdm subjects (p=0.07). a total of 56.8% of gdm patients were compared with 35.8% of control group which had vitamin d deficiency and the difference was significant (p= 0.02). there was no significant association between vitamin d levels and fasting glucose, insulin and hba1c. vitamin d levels were inversely correlated with clothing style, parathyroid hormone levels, dental problems and muscle cramps. conclusions: the association of maternal vitamin d status with the markers of glucose metabolism in pregnancy needs prospective studies