Serum level of Lactate dehydrogenase, Homocystein, Hemoglobin and platelet in preeclampsia

Objectives: pre-eclampsia affects approximately 5–8% of pregnant women. the aim of this study was to compare the serum level of lactate dehydrogenase (ldh), homocystein, hemoglubin and platelet in pregnant women diagnosed as pre-eclampsia and a normal group in gorgan city, northeastern iran from 2007-2008. methodology: in this case control study, 50 cases of pre-eclampsia were compared with the control group women hospitalized in dezyani hospital. pre-eclampsia criteria were: blood pressure more than or equal to 140/ 90 mm hg and proteinuria greater or equal to 300 mg/ 24 hours urine sample in the third trimester. hemoglobin, platelet, ldh and hemocystein were measured. data were analyzed by the mean of spss-14 program & chi-2 or t-student were used. results: the difference of bmi and family incomes was significant between two groups (p-value<0.01). ldh level was not statistically different between healthy and pre-eclamptic individuals. six cases (12%) in controls and 9 cases (18%) in pre-eclamptic group had thrombocytopenia (p-value>0.01). hemocystein level was more than normal range in five patients with pre-eclampsia (p-value<0.001). conclusions: in this study, hemocystein level was significantly higher in pre-eclampsia patients but ldh, hemoglobin and platelet level had no significant difference.