Pseudohypoparathyroidism Type-II with Striopallidodentate calcification with positive anti glutamic acid decarboxylase antibody and seizures

Pseudohypoparathyroidism (php) is disorder characterized by biological insensitivity of parathyroid hormone (pth) at tissue level. there are several sub types of php have been described with identical features of increased resistance to pth by kidney and bone with resultant biochemical features of increased level of pth, hypocalcemia and hyperphosphatemia. we describe unique case of subtype of pseudohypoparathyroidism (php) type ii complicated by massive intracranial calcification of striopallidentate (spd) system resulting in seizure activity. this case is quite unique and worthwhile to report linking php type ii and intra cranial calcification