Relationship between 24-hour mean pulse pressure and the cardiac function in the elderly with isolated systolic hypertension

Objective: to investigate the effect of mean pulse pressure during 24 hours on cardiac function in the elderly with isolated systolic hypertension.methodology: one hundred seventy two elderly patients with isolated systolic hypertension were enrolled to determine mean pulse pressure by monitoring 24-hour ambulatory blood pressure and to analyze the cardiac function by nuclide cardiac blood pool imaging.results: twenty four hours mean pulse pressure negatively correlated with left ventricular ejection fraction (lvef) ( r = - 0.46, p < 0.01 ), and also with peak filling rate (rfr) ( r = - 0.41, p < 0.05). the greater the mean pulse pressure, the worse the cardiac function (p < 0.01).conclusion: the 24-hours mean pulse pressure was an important factor predicting risk for cardiac disfunction in the elderly with isolated systolic hypertension