Clinical osteoporosis probability scoring system: Selection of menopausal women for bone densitometry screening

Objectives: to formulate a clinical scoring system for evaluating people at risk of osteoporosis before ordering bone mass densitometry. methodology: eighty two probable clinical osteoporosis related factors were checked in 325 females referred for bone mass densitometry testing in hamadan province, iran. the statistical modeling resulted in a clinical osteoporosis probability (cop) scoring system based on 9 factors including: fracture history, drug therapy with thyroid hormone, corticosteroids, estrogen, ca-vitd, number of children, age, bmi and the number of menopausal years. results: osteoporosis was found in 62.2%. the osteoporosis probability scoring system cutoff value of 26.8 was selected with 89% sensitivity, 63% specificity, youden factor of 0.53 and lr=2.4. in this score, osteoporosis probability was 98%. area under the curve in roc curve of osteoporosis probability scoring system was 81.4%. conclusion: clinical osteoporosis probability scoring system with a 26.8 cutoff value is suggested for osteoporosis prescreening using bone mass densitometry test.