Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome

Objective: to determine the biochemical and hormonal differences in polycystic ovary syndrome (pcos) patients with and without polycystic ovary (pco) morphology and to evaluate the outcomes resulting from those differences. methods: the study included a total of 83 patients with pcos; 43 of them had pco morphology (group-i) and 40 did not (group-ii). serum ldl,hdl,total cholesterol,triglyceride (tg),total testosterone (t),follicle stimulating hormone (fsh),luteinizing hormone (lh),17b-estradiol (e2),prolactin (prl),thyroid stimulating hormone (tsh),sex hormone binding globulin (shbg),glucose and insulin levels were determined. homoeostatic model assessment insulin resistance (homa-ir) index was calculated. results: the two groups were similar with respect to bmi. the systolic and diastolic blood pressure measurements of group-i were significantly lower (p<0.01). serum mean level of lh (p=0.026) and the mean lh/fsh (p=0.001) level of group-i were significantly higher than group-ii. the total cholesterol and triglyceride levels of group-i were significantly lower (p<0.05,p<0.01). the mean homa-ir level of group-i was significantly lower than group-ii (p=0.004). conclusions: the group without pco morphology had a higher risk than the other group in terms of increased insulin resistance,dyslipidemia and cardiovascular diseases due to effects of hyperandrogenism. © 2016,professional medical publications. all rights reserved.