Plasma BNP level combined with surgical Apgar score to predict operative major cardiac adverse events in malignant obstructive jaundice patients

Objective: to investigate the predictive effect of major adverse cardiac events (mace) in malignant obstructive jaundice (oj) patients using plasma brain natriuretic peptide (bnp) level and surgical apgar scoring (sas) system. methods: forty one malignant oj patients undergoing surgical treatments were studied at a single center. pre-and postoperative plasma bnp level,total bilirubin (tbil) and data of cardiac function (hr,cvp,ci,lvef%) were detected,the sas was calculated during the surgery,the relationship of both plasma bnp level and sas with mace after surgery was analyzed. results: thirteen patients out of 41 (31.71%) experienced mace without cardiac death. oj patients had a higher plasma bnp level than baseline before operation (191.61±105.76 pg/ml vs 175 pg/ml,p<0.05),the cardiac function data was improved (cvp: t=4.761,p=0.000; ci: t=3.539,p=0.001; lvef%: t=3.632,p=0.001) after the operation. patients with lower sas had increasing incidence of mace after surgery. conclusion: malignant oj patients with higher preoperative bnp level and lower surgical apgar score were identified at high risk of mace after surgery. © 2016,professional medical publications. all rights reserved.