Comparison of serum lipid profile in Type-2 Diabetics with and without retinopathy in Pakistani population

Objective: to compare serum cholesterol,tg,hdl-c and ldl-c concentrations between type-2 diabetes mellitus (dm) patients with retinopathy and without retinopathy and to study association between various modifiable risk factors of diabetic retinopathy (dr). methods: the study included 300 patients with type 2 dm; 140 of them were without dr (group-i) and 160 were with dr (group-ii). serum total cholesterol,ldl-c,hdl-c,and tg levels were determined. spss 17.0 for windows was used for statistical analysis. results: overall,mean age of study population was 48.86 ± 5.62 years. subjects with dr were older (p < 0.018),had higher fasting plasma glucose (p < 0.01) and higher hba1c (p <0.01) concentrations compared with those without dr. analysis of serum cholesterol,ldl-c,hdl-c and tg among subgroups of patients with no dr,with npdr and pdr showed statistically significant difference (p <0.01). there was strong positive correlation of severity of dr with bsf,hba1c,serum ldl-c,total cholesterol and tg. conclusion: the serum cholesterol,tg,hdl-c and ldl-c concentrations were found to be significantly deranged in patients with dr as compared to those without dr. © 2016,professional medical publications. all rights reserved.