Clinical features and risk factors for irritable bowel syndrome in Migraine patients

Objective: clinical and basic research increasingly suggests a correlation between migraine and irritable bowel syndrome (ibs). in this study,we aimed to explore the clinical features and risk factors for ibs in migraine patients. methods: this was a retrospective,cross-sectional study. a total of 1,112 consecutive patients from the internal medicine and emergency departments of three hospitals from june 2014 through 2016. a comprehensive interviewer-administered questionnaire was designed based on the international classification of headache disorders,3rd edition (beta version). results: the response rate was 94.6%. among 1,052 participants,287 suffered from migraine (27.3%) and 312 suffered from ibs (29.7%). a total of 79 patients suffered from both migraine and ibs (comorbidity rate: 7.5%). the migraine cohort exhibited a higher frequency of ibs than did the comparison cohort at baseline (p<0.05). migraine patients with higher headache frequency,longer length of headache history,and anxiety disorders were more likely to also suffer from ibs (p=0.015). there were no significant differences between the two groups in age,sex,family history,duration of headache attack,migraine aura,headache intensity,or depression disorders (p>0.05). multiple regression analysis indicated length of headache history and headache frequency were associated with ibs. conclusion: migraine patients with a long headache history,recurrent episodic headache attacks,and anxiety were more likely to have ibs. © 2017,professional medical publications. all rights reserved.