hsCRP and ET-1 expressions in patients with no-reflow phenomenon after percutaneous coronary intervention

Objective: to explore hscrp and et-1 expressions in patients with no-reflow phenomenon after percutaneous coronary intervention (pci). methods: a total of 136 patients with single coronary artery disease receiving pci were divided into a reflow group and a no-reflow group to compare the level use of et-1 alone with combined level of et-1 and hs-crp in pci regarding sensitivity,specificity,positive and negative predictive values and accuracy for postoperative no-reflow. the study was conducted between 2014-2016 at our hospital. results: postoperative levels of et-1 and hs-crp in no-reflow group were significantly higher than those of reflow group (p<0.05). et-1 level of reflow group peaked three hours after pci and then declined. serum level of hs-crp decreased most obviously within three hours after pci in reflow group and three hours -three days after pci in no-reflow group. left ventricular end-diastolic diameters of both groups after pci were apparently lower than those before pci,without significant inter-group difference (p>0.05). left ventricular end-systolic diameters and left ventricular ejection fractions of both groups evidently increased after pci,without significant inter-group differences either (p>0.05). corrected timi frame count (ctfc) and wall motion score index of reflow group after pci were significantly lower than those of no-reflow group (p<0.05). et-1 level was positively correlated with ctfc (p<0.05). multivariate linear regression showed hs-crp was negatively correlated with the serum level (p<0.05) (r=-0.34). conclusion: hscrp and et-1 levels significantly increased in patients with no-reflow phenomenon. © 2017,professional medical publications. all rights reserved.