A comparison of anxiety and depression between pre-dialysis chronic kidney disease patients and hemodialysis patients using hospital anxiety and depression scale

Objective: to compare frequency of anxiety and depression between pre-dialysis chronic kidney disease (ckd) and hemodialysis patients (esrd) in pakistan. methods: this study was conducted in an out-patient department and hemodialysis unit of sharif medical city hospital. inclusion criteria included age above 18 years and a diagnosis of ckd including both pre-dialysis ckd and esrd patients. patients were screened for anxiety and depression using hospital anxiety and depression scale (hads). results: a total of 156 patients were included in the study. out of these patients,81 (51.9%) had esrd and 75 (48.1%) had pre-dialysis ckd. mean age of all patient was 47.3±18.3 years,96 (61.5%) were males and 60 (38.5%) were females. median duration of renal disease was 16 months (iqr 8-36 months). anxiety and depression were present in 111 (71.2%) and 113 (72.4%) of all patients respectively. moderate to severe anxiety and depression were present in 54 (34.6%) and 60 (38.5%) patients respectively. in multiple logistic regression model,after adjusting for other variables,esrd vs. pre-dialysis ckd was significantly associated with moderate to severe depression (aor 2.26 (1.1-5.1). conclusion: both anxiety and depression are common in pre-dialysis ckd and esrd patients. patients with esrd have higher frequency of depression compared to pre-dialysis ckd patients. © 2017,professional medical publications. all rights reserved.