Synthesis, Characterization and Catalytic Behavior of some L-Hydroxyprolines Dimers for Asymmetric Aldol Reaction
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نویسنده
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Al-Momani Lo’ay A.
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منبع
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jordan journal of chemistry - 2014 - دوره : 9 - شماره : 4 - صفحه:289 -300
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چکیده
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Diesters derived from 4-l-hydroxyproline and malonic, succinic, glutaric or adipic acid are prepared and employed as enantioselective catalysts in the aldol reaction of pnitrobenzaldehyde with acetone. the catalytic properties are tested using different concentrations of the catalysts. a conversion of 50-100% and enantiomeric excess (ee) values of 74-84% are obtained with 20 % mol of the catalyst.
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کلیدواژه
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Non-proteinogenic amino acid; organocatalysis; hydroxyproline; asymmetric aldol reaction
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آدرس
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Tafila Technical University, Department of Chemistry, Jordan
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پست الکترونیکی
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loay.al-momani@daad-alumni.de
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