Synthesis and Supramolecularity of Non-Centrosymmetric Proton Transfer Compound 2-Aminopyridinum Picolinoate

The proton-transfer compound 1 was prepared by mixing equimolar amounts of picolinic acid with 2-aminopyridine. its crystal structure was determined by single-crystal x-ray diffraction. compound 1 was ionic, with proton transfer occurring to the aromatic nitrogen of the 2-aminopyridine moiety. supramolecular synthons including different motifs of hydrogen bonding, ion-pairing interactions, and non-centrosymmetric heteromer existed in the crystal structure were carefully investigated and presented in term of crystal engineering and host-guest chemistry. compound 1 crystallizes in the space group p2(1)/n of the monoclinic system with unit cell parameters of: a = 8.7714(12) å, b = 12.1579(17) å, c = 10.8546(15) å, with α = 90°, β = 110.100(4)°, and γ = 90°.