بررسی متابولیتهای خونی و ارتباط آن با بیماری مسمومیت آبستنی در میش های ایرانی دو رگ

The aim of this study was to investigate the serum total protein, calcium, glucose, cholesterol, phosphorus, creatinine, urea and magnesium concentrations in the crossbreed ewes during late pregnancy. all blood metabolites were determined in 90 healthy baluchi×moghani and ghezel×baluchi ewes with single or twin lambs. blood metabolites were assessed by spectrophotometer methods by using commercial kits (pars azmon, iran). while serum calcium, glucose, creatinine and urea levels were lower, serum cholesterol, phosphorus and magnesium levels were higher in twin-bearing sheep, compared to single-bearing sheep on late of pregnancy. mean comparison blood parameters among twin and single bearing ewes showed significant differences (f=4.46, p < 0.05) just for total protein concentrations. spearman correlation tests of the results among metabolic profiles showed a positive and significant (p < 0/001) correlations between calcium and creatinine concentrations (rs=0.3), between glucose and magnesium concentrations (rs=0.5), and between urea and phosphorus concentrations (rs=0.3). also, there was negative and significant (p < 0/001) correlations between total protein with cholesterol and phosphorus levels (rs=- 0.28), urea with calcium (rs=- 0.4) and creatinine levels (rs=- 0.55), and glucose with phosphorus (rs=- 0.46) and urea levels (rs=- 0.37). it is concluded that the presence of significant correlations among blood parameters in pregnant ewes could be useful to diagnosis abnormal metabolic sates and pregnancy toxemia.