determining the relationship between maternal and neonatal vitamin d serum levels in term infants with and without sepsis

Objective: to investigate the relationship between maternal and neonatal vitamin d serum levels in term infants with and without sepsis. materials and methods: this is a case-control study with 320 participants which include, 80 mothers and babies with neonatal sepsis and 80 control mothers and babies without neonatal sepsis that included in  their quantitative vitamin d levels were compared with each other survey. results: demographic and clinical characteristics of infants (age at admission, gender) and mothers (age, education level) were recorded. blood samples were taken to check serum vitamin d levels of these babies along with their mothers. vitamin d levels were classified as deficiency less than 10 ng/ml, moderate deficiency 10-30 ng/ml, mild deficiency 20-30 ng/ml and normal 100-30 ng/ml.33 (41.3%) of the infants born in the neonatal sepsis group and 45 (56.3%) of the control infants were male. using fisher’s exact test, no significant difference was found between the two groups in terms of gender distribution, p=0.082. the median age of infants in the neonatal sepsis group was 5 (3-9) days and in the control group was 5 (4-6) days. the mean (age of mothers in the patient group was 29.6 (6.4) years and in the control group was 29.7 (5.6) years. the median range of maternal vitamin d levels in the neonatal sepsis group was 23.8 (15.0-30.0) and 28.6 (17.1-34.0) ng/ml in the control group. according to the mann-whitney u statistical test, the vitamin d level of mothers in the neonatal sepsis group was significantly lower than that of the group was the control (p=0.020). conclusion: according to the result of the mann-whitney u test, the vitamin d level of mothers in the neonatal sepsis group was significantly lower than the control group (p=0.020). mother’s vitamin d level maybe related to the incidence of neonatal sepsis.