could maternal vitamin d concentration affect cervical length in mid-pregnancy? a report from an iranian tertiary center

Objective: this descriptive-analytic cross-sectional study aimed to figure out whether maternal serum vitamin d concentration correlates with cervical length measurement in mid-gestation or not. materials and methods: during jun-jan 2021, 213 pregnant women at 18-22 weeks of gestation were investigated. first, demographic features were obtained then, maternal serum vitamin d concentration was measured by enzyme-linked immunoassay and cervical length was measured via transvaginal sonography according to fetal maternal foundation guideline and appropriate statistical test was used to analyze the correlation between maternal vitamin d level and cervical length in mid-pregnancy. results: it was shown that 29.6% and 25.4% of participants had vitamin d deficiency and insufficiency, respectively. spearman’s test found no significant correlation between maternal vitamin d level and cervical length in mid-pregnancy. moreover, cervical length and maternal vitamin d level had no association with maternal bmi. conclusion: although maternal vitamin d level and its sufficiency status was not associated with cervical length in mid- pregnancy, as a trend toward decreased maternal serum vitamin d level by advancing gestational age was observed. it may be concluded that it is prolonged vitamin d deficiency during gestation that may lead to cervical length shortening and subsequent preterm delivery later in gestation.