comparative analytical study of dinoprostone gel and hyaluronidase injection for induction of labour in term primigravida in tertiary rural medical centre of western uttar pradesh

Objective: to compare the efficacy of intracervical dinoprostone gel and hyaluronidase injection for induction of labour in term primigravida. materials and methods: this is a hospital based analytical prospective interventional study conducted in a rural tertiary care centre over a period of 18 months. a total of 70 patients who required induction of labour for one or another reason with bishop score of less than 6 were included in the study. all the cases were randomly divided into two groups, group a received dinoprostone gel and group b received hyaluronidase injection. chi square test & unpaired t test were applied for statistical analysis. results: time interval from induction to active phase of labour was comparatively shorter in group a than in group b (10.74 ± 6.17 vs 15.94 ± 7.1) and the difference was significant (p= 0.001). time interval from induction to delivery time was comparatively shorter in group a than group b (14.84 ± 8.86 vs 21.33 ± 7.86) and difference was significant (p= 0.009). maternal complications were more common in group a as compared to group b. conclusion: this study showed that labour could be accelerated significantly by intracervical injection of hyaluronidase. hyaluronidase injection has less maternal and fetal side-effects as compared to dinoprostone gel and can be a good choice for induction of labour