assessment of the impact of diflubenzuron on the inhibition of adult emergence in aedes aegypti (diptera: culicidae) from hormozgan province, iran, 2025

Background: the presence of aedes aegypti in iran and the risk of transmitting viral diseases, such as dengue and zika, underscore the importance of evaluating effective vector control methods. methods: this study investigated the effectiveness of diflubenzuron, an insect growth regulator that inhibits chitin syn­thesis, in preventing adult emergence of ae. aegypti larvae from hormozgan. the concentrations of 0.03, 0.06, 0.12 and 0.24 mg/l of 25% wettable powder formulations of diflubenzuron were used, according to who protocols. results: diflubenzuron was highly effective at 0.24 mg/l, achieving 98% emergence inhibition (ei50=0.053 mg/l, ei90=0.146 mg/l). at lower concentrations, e.g., 0.12 mg/l, emergence inhibition decreased to 83%, indicating a clear concentration-dependent reduction in efficacy. larvae exposed to sublethal doses displayed abnormal movements and reduced responses to stimuli. conclusion: this experiment supports diflubenzuron's potential as an effective larvicide for vector control programs in iran. however, field trials and resistance monitoring are recommended before widespread implementation.