lessons from an 11-year retrospective cohort study of escherichi coli causing uti in imam hospital ardabil, iran

Background and objectives: the global problem of urinary tract infections (utis) caused by antibiotic-resistant bacteria is due to limited treatment options. this study aimed to examine the prevalence, etiology, and management implications of escherichi coli causing uti at imam hospital ardabil, iran.materials and methods: 2340 samples of retrospective data on e. coli causing utis were collected at imam hospital in ardabil, iran, spanning from 2012 to 2022. the samples were cultured and isolated, and their antibiotic susceptibility was determined using standard laboratory methods and data were then organized and systematically categorized using python.results: it was found that the lowest level of resistance was related to nitrofurantoin, followed by imipenem. in 2018, the number of e. coli patients resistant to trimethoprim was the highest. cephalexin and ciprofloxacin trends indicate the reduction of the line during this retrospective period. there was a significant correlation between wards and some antibiotics like cefepime, cefotaxime, ceftazidime, and trimethoprim (p-value <0.05).conclusion: significant correlations were identified between specific hospital wards and resistance to antibiotics. these findings underscore the need for continuous surveillance and tailored antibiotic stewardship programs to combat the rising trend of antibiotic resistance.