adenovirus-5 and adenovirus-37 seropositivity in obese patients

Background and objectives: obesity is a major health issue linked to conditions like diabetes, hypertension, and hyperlipidemia. infectobesity suggests that certain microorganisms may contribute to obesity. human adenovirus serotypes, particularly human adenovirus type-36 (hadv-36), human adenovirus type-5 (hadv-5), and human adenovirus type-37 (hadv-37), are thought to influence body fat regulation. this study investigates the relationship between immunoglobulin g (igg) positivity for hadv-5 and hadv-37 and obesity, aiming to provide data on the infectious etiology of obesity.materials and methods: blood samples separated into serums from obese (bmi ≥30) and non-obese (bmi 18.5-25) individuals were tested for hadv-5 and hadv-37 seropositivity using elisa kits and seropositivity rates between the groups were compared.results: hadv-37 antibody positivity was significantly higher in obese patients (39/48) compared to the control group (24/42) (p=0.011). for hadv-5, antibody positivity was similar in both groups (26 individuals each) with no significant difference (p=0.461). no significant gender-related differences were found for either serotype.conclusion: the study suggests hadv-37 may be associated with obesity, while no such relationship was found for hadv-5. there was no gender association for either serotype. these results align with existing literature on hadv-37, but further research is needed to confirm the link between adenoviruses and obesity and explore potential treatment options.