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surveying the chemical composition and antibacterial activity of essential oils from selected medicinal plants against human pathogens
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نویسنده
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osanloo mahmoud ,ghaznavi ghazal ,abdollahi abbas
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منبع
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iranian journal of microbiology - 2020 - دوره : 12 - شماره : 6 - صفحه:577 -583
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چکیده
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Background and objectives: essential oils (eos) with different biological activities, such as antibacterial properties, are a valuable resource for developing new drugs. materials and methods: ingredients of six medicinally important eos, including artemisia dracunculus, anethum graveolens, citrus limon, citrus sinensis, cinnamomum zeylanicum and zingiber officinale, were identified using gc-ms analysis. moreover, their five major compounds were also listed. furthermore, the half-maximal inhibitory concentration (ic50) against four important human bacteria was also investigated using the 96-well plate microdilution. results: c. sinensis eo with ic50 of 1.0 and 4.7 mg.ml^-1 have the most effect on the growth of s. aureus and p. aeruginosa. moreover, eos of cinnamomum zeylanicum (ic50: 1.0 mg. ml^-1) and artemisia dracunculus (ic50: 1.3 mg.ml-1) significantly showed better inhibitory effect on e. coli and k. pneumoniae. conclusion: these eos could be used for developing inexpensive, potent, and green antibacterial agents.
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کلیدواژه
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essential oil; antibacterial activity; pathogens; microdilution
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آدرس
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fasa university of medical sciences, noncommunicable diseases research center, school of advanced technologies in medicine, department of medical nanotechnology, iran, fasa university of medical sciences, school of medicine, department of medical biotechnology, iran, fasa university of medical sciences, school of medicine, department of microbiology, iran
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پست الکترونیکی
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a.abdollahi360@yahoo.com
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Authors
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