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Studying the Effect of a Maltitol Solution on the Stability of Water Soluble Vitamins
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نویسنده
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Sakeer Khalil ,Al-Zein Hind
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منبع
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jordan journal of pharmaceutical sciences - 2012 - دوره : 5 - شماره : 2 - صفحه:131 -140
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چکیده
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The stability of vitamins in a liquid dosage form is still considered a challenge to pharmacists to obtain a stableformula. the objective of this study was to formulate multi-water soluble vitamin oral solutions, study thestability of this formulation at accelerated conditions 40 ± 2 oc / 75% ± 5% rh for two months and investigatethe effect of the ph and the percent of a maltitol solution on the stability of the vitamins. results showed thatusing a 30% maltitol solution gave a pronounced improvement in the stability of vitamins compared with asorbitol solution, and the ph had a critical role on the stability of vitamins so the vitamins had an optimumstability at ph between 3.5 – 4
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کلیدواژه
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water soluble vitamins ,maltitol solution ,accelerated condition ,sorbitol solution
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آدرس
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The Syrian International Private University for Science and Technology, Faculty of Pharmacy, Department of Pharmaceutics and Pharmaceutical Technology, Syria, Damascus University, Faculty of Pharmacy, Department of Pharmaceutics and Pharmaceutical Technology, Syria
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Authors
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