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Epoxidationof Ferutinin by Different Fungi and Antibacterial Activity of its Metabolite
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نویسنده
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Choudhary M. Iqbal ,Mohammad Mohammad Yasin ,Musharraf Syed Ghulam ,ur-Rahman Atta
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منبع
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jordan journal of pharmaceutical sciences - 2013 - دوره : 6 - شماره : 1 - صفحه:23 -29
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چکیده
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Structural transformation of the sesquiterpene ester, ferutinin (1), by suspended fungal cultures of aspergillus niger, rhizopus stolonifer, and fusarium lini, resulted in the formation of a metabolite. this metabolite was identified as ferutinin α-epoxide (2), by different spectroscopic techniques. metabolite 2 showed a good antibacterial activity against staphylococcus aureuscompared to ferutinin (1) keywords: sesquiterpene ester, ferutinin, fungal transformation, aspergillus niger, rhizopus stolonifer,fusarium lini, ferutinin α-epoxide, epoxidation, staphylococcus aureus, antibacterial activity.
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آدرس
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University of Karachi, H E J Research Institute of Chemistry / International Center for Chemical and Biological Sciences, Pakistan. King Saud University, College of Science, Department of Chemistry, Saudi Arabia, University of Karachi, H E J Research Institute of Chemistry / International Center for Chemical and Biological Sciences, Pakistan, University of Karachi, H E J Research Institute of Chemistry / International Center for Chemical and Biological Sciences, Pakistan, University of Karachi, H E J Research Institute of Chemistry / International Center for Chemical and Biological Sciences, Pakistan
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Authors
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