Successful hemodialysis and renal transplantation in combined factors of V and VIII deficiencies

Introduction: the prevalence of rare bleeding disorders, including combined factor v+viii deficiency are higher in iran than in developed countries. there are only a few reports which have been written concerning kidney transplantation in the patients suffering from these disorders. case report: a 22-year old girl, with a known case of combined factor v+viii deficiency, a history of bladder stone surgery, postoperative bleeding and a need for hemodialysis due to renal failure was admitted for allograft kidney transplantation. the patient received fresh-frozen plasma and factor viii, according to individualized protocol before, during and after the course of the transplantation. the function of the grafted kidney was very good nine months post-transplantation. discussion: only heparin was used during hemodialysis. it has been shown that allograft kidney transplantation can be performed in rare bleeding disorders with good replacement therapy without any complications.