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The emerging role of immunomodulatory agents in fetal hemoglobin induction
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نویسنده
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Dehghani Fard Ali ,Kaviani Saeid ,Saki Najmaldin ,Mortaz Esmaeil
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منبع
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international journal of hematology-oncology and stem cell research - 2012 - دوره : 6 - شماره : 4 - صفحه:35 -36
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چکیده
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Beta-thalassemia is considered as genetic disorder characterized by insufficiency or absence of β-globin gene expression with accumulation of α-globin chains in erythroid precursor cells resulting in ineffective erythropoiesis (1, 2). recently, attempt for augmentation of fetal hemoglobin (hbf) production has been established as a novel therapeutic strategy in blood transfusion independent beta-thalassemia.
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آدرس
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tarbiat modares university, Faculty of Medical Sciences, Department of Hematology, ایران, tarbiat modares university, Faculty of Medical Sciences, Department of Hematology and Blood Banking, ایران, ahvaz jundishapur university of medical sciences, Research Center of Thalassemia & Hemoglobinopathy, ایران, Utrecht University, Faculty of Sciences, Utrecht Institute for Pharmaceutical Sciences, Division of Pharmacology and Pathophysiology, Netherlands
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Authors
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