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T-cell Acute Lymphoblastic Leukemia with del (7) (q11.2q22) and Aberrant Expression of Myeloid Markers
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نویسنده
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Ahmadzadeh Ahmad ,Saedi Sajedeh ,Jaseb Kaveh ,Asnafi Ali Amin ,Alghasi Arash ,Saki Najmaldin
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منبع
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international journal of hematology-oncology and stem cell research - 2013 - دوره : 7 - شماره : 4 - صفحه:40 -44
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چکیده
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T cell acute lymphoblastic leukemia (all) is an invasive disease with a higher incidence in children and adolescents. in terms of immunophenotype, t-all is positive for cd2, cd7, cd34 and hla-dr, and the level of these markers is increased with increasing age. in addition, the myeloid markers (cd13, cd33) are sometimes expressed in t-all. in this study, we introduce a rare case of a 28-year-old woman with t-all with aberrant expression of myeloid markers (cd13), without lymphadenopathy and with 94% blasts in bone marrow specimens. the patient has the rare karyotype of 46,xx del(7)(q11.2q22). the presence of del7 is a rare phenomenon in t-all.
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کلیدواژه
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Acute lymphoblastic leukemia ,Myeloid ,T cell
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آدرس
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ahvaz jundishapur university of medical sciences, Cancer, Petroleum and Environmental Pollutants Research Center, ایران, ahvaz jundishapur university of medical sciences, Research Center of Thalassemia & Hemoglobinopathy, ایران, ahvaz jundishapur university of medical sciences, Research Center of Thalassemia & Hemoglobinopathy, ایران, ahvaz jundishapur university of medical sciences, Research Center of Thalassemia & Hemoglobinopathy, ایران, ahvaz jundishapur university of medical sciences, Research Center of Thalassemia & Hemoglobinopathy, ایران, ahvaz jundishapur university of medical sciences, Research Center of Thalassemia & Hemoglobinopathy, ایران
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Authors
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