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Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies
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نویسنده
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lajimi Abdolreza Ardeshiry ,Farshdousti Hagh Majid ,Saki Najmaldin ,Mortaz Esmaeil ,Soleimani Masoud ,Rahim Fakher
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منبع
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international journal of hematology-oncology and stem cell research - 2013 - دوره : 7 - شماره : 1 - صفحه:15 -33
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چکیده
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Multiple sclerosis is an inflammatory disease of the central nervous system in which t cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. the recent advances in stem cell therapies may serve as potential treatments for neurological disorders. there are broad types of stem cells such as neural, embryonic, mesenchymal and hematopoietic stem cells with unprecedented hope in treating many debilitating diseases. in this paper we will review the substantial literature regarding experimental and clinical use of these stem cells and possible mechanisms in the treatment of ms. these results may pave the road for the utilization of stem cells for the treatment of ms.
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کلیدواژه
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Multiple sclerosis ,Stem cells therapy ,Human embryonic stem cells ,Hematopoietic stem cells ,Mesenchymal stem cells ,Neural stem cells
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آدرس
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Stem Cell Technology Research Center, Stem Cell Biology Department, ایران, tabriz university of medical sciences, Faculty of Medicine, Division of Laboratory Hematology and Blood Banking, ایران, ahvaz jundishapur university of medical sciences, Research Center of Thalassemia & Hemoglobinopathy, ایران, Utrecht University, Faculty of Sciences, Utrecht Institute for Pharmaceutical Sciences, Division of Pharmacology and Pathophysiology, Netherlands, tarbiat modares university, Faculty of Medical Science, Hematology Department, ایران, ahvaz jundishapur university of medical sciences, Toxicology Research Center, ایران
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Authors
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