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cardiac considerations in hematopoietic stem cell transplantation (hsct) for transfusion-dependent thalassemia: a review
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نویسنده
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nateghi saeed ,rasooli aziz ,moadabshoar leila ,panahi zahra ,rostami mohammad reza
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منبع
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international journal of hematology-oncology and stem cell research - 2025 - دوره : 19 - شماره : 1 - صفحه:69 -74
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چکیده
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Hematopoietic stem cell transplantation (hsct) is considered a potentially curative treatment for several malignant and non-malignant hematologic disorders including transfusion-dependent thalassemia (tdt). however, hsct is associated with short-term and long-term complications. one of the recognized causes of morbidity and mortality in tdt patients is heart-related complications. additionally, cardiac involvement is likely to be more common in patients who proceed to hsct. so the risks of cardiac complications should be carefully weighed against the advantages of the primary disease cure. this review aims to discuss the cardiac considerations that should be kept in mind in tdt patients going through the path of hsct.
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کلیدواژه
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transfusion-dependent thalassemia; hematopoietic stem cell transplant; cardiotoxicity; cardiomyopathy; graft-versus-host disease
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آدرس
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tehran university of medical sciences (tums), baharloo hospital, school of medicine, department of cardiology, iran, tehran university of medical sciences (tums), school of medicine, department of emergency medicine, iran, ministry of health and medical education, prevention and cancer control group, iran, tehran university of medical sciences (tums), school of medicine, department of perinatology, iran, tehran university of medical sciences, research institute for oncology, hematology and cell therapy (riohct), cell therapy and hematopoietic stem cell transplantation research center, iran
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پست الکترونیکی
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mr.rostami2@gmail.com; mr-rostami@tums.ac.ir
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Authors
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