pure biclonal hairy cell leukemia–apt diagnosis with multicolor flow cytometry

Hairy cell leukemia (hcl) is a rare b-cell neoplasm that constitutes around 2 percent of all lymphoid leukemias and occurs more frequently in elderly males. the usual triad of hcl includes pancytopenia, splenomegaly, and hairy cells in the bone marrow. this is a case of an atypical presentation of biclonal hcl diagnosed on flow cytometry; the existence of biclonal hcl is extremely rare with very few case reports. pure biclonal hcl should be regarded as an extraordinary finding among the so-called composite lymphomas.