GCK Mutation in a Child with Maturity Onset Diabetes of the Young, Type 2

Background: maturity onset diabetes of the young type 2 (mody) is an inherited disorder due to mutations in glucokinase (gck) gene, which lead to mild fasting hyperglycemia. case presentation: herein an otherwise healthy 9-year old boy with hyperglycemia is presented in whom the diagnosis of mody2 was suspected. genetic studies showed heterozygous inactivating gck gene mutation in exon 8 (c.1010dela) in this patient. the same mutation was found in his father as well. the patient received some dietary advices without any medication. conclusion: the identification of gck mutation and diagnosis of mody2 helps the clinicians to predict the disease course, prognosis and to exclude other types of diabetes.