could covid-19 trigger presentation or exacerbation of vasculitides? (a 14-year-old girl with newly diagnosed gpa after covid-19 infection)

Introduction: granulomatosis with polyangiitis (gpa) is a kind of anti-neutrophil cytoplasmic antibody (anca)-associated vasculitis(aav), which involves small-to-medium-sized vessels. besides, gpausually involves the upper and lower respiratory tract, and alsocauses necrotizing glomerulonephritis. the involvement of the heart and gastrointestinal (gi) tract in gpa is unusual, and these areatypical places of this vasculitis.case presentation: a14-year-old girl with a newly diagnosedgpaafter afflicting with covid-19 infection presented with st-elevationmyocardial infarction (mi), gi perforation, and intracranial hemorrhage.conclusions: although gpa is rare in the pediatric population, it might occur in this age group and could involve multiple organsystems.