cast bronchitis in a cystic fibrosis child: experience with direct instillation of dornase alfa as an adjunct treatment agent

Introduction: lobar atelectasis is one of the common problems in patients with cystic fibrosis and can be a cause of respiratory symptoms in these patients even in the absence of bacterial infection. case presentation: hereweintroduce a 9-year-oldboy with cystic fibrosiswhohadmanyadmissions because of respiratory distress due to lung collapse mainly caused by plastic bronchitis. conclusions: in a number of patients with cystic fibrosis, lobar atelectasis is seen which is resistant to medical treatments. early fiberoptic bronchoscopy as a measure for mechanical removal of the blocking agent and sometimes direct injection of drugs like dornase alfa into the bronchus is a successful modality in the treatment of lobar collapses in chronic pulmonary diseases.