Juvenile Dermatomyositis;Clinical and Laboratory Assays

Objective: objective: juvenile dermatomyoistis (jdms) involves children rarely. our purpose of thisstudy is to detect clinical and laboratory aspects of this disorder and its treatment in khorasanprovince.material & methods: a 10-years retrospective study performed on medical records of all patientswith jdms in a medical center in mashhad. data was analyzed with statistical measures includingspss and excel.findings: 18 patients had djms during 10 years. there was a female to male predominance (1.25/1).the mean age of patients was 12.1 years. muscular weakness was the most common presentingsymptom. skin involvement including heliotrope rash and gottron papules were detected in mostpatients. elevated muscular enzymes were an important finding in many cases. emg, and musclebiopsy in those cases performed, showed abnormal results. seventeen (94.5%) of patients respondedto oral prednisolon therapy.conclusion: according to clinical manifestations and laboratory findings, in particular muscularenzyme assays, a timely diagnosis and treatment with oral prednisolon can improve the diseasedramatically and reduce morbidity and mortality rates as well.