Isolated Hemihyperplasia in an Infant: An Overlooked Sign for Wilms Tumor Development

Background: children with overgrowth syndromes including isolated hemihyperplasia have an increased risk for developing embryonal tumors, particularly wilms’ tumor and hepatoblastoma. screening with sonography has been suggested as a method of identifying these tumors while they are still at an early stage. case presentation: we describe an infant diagnosed with wilms tumor in whom isolated hemihyperplasia had been overlooked by several physicians prior to the tumor diagnosis.conclusion: we recommend tumor surveillance for all patients with beckwith-wiedemann syndrome and isolated hemihyperplasia at least for the first six years of life since full molecular characterization of every patient is not readily available.