مقایسه تاثیر نبولایزر گل ختمی و اکالیپتوس بر شدت سرفه مبتلایان به کووید-19: کارآزمایی بالینی

زمینه و هدف: یکی از شایعترین عارضه‌های مهم کووید-19 سرفه است، پژوهش حاضر با  هدف مقایسه تاثیر نبولایزر گیاه گل ختمی و اکالیپتوس بر شدت سرفه در بیماران مبتلا به کووید-19 طراحی شده است.روش بررسی: در این کارآزمایی بالینی تصادفی از دی ماه 1400تا خرداد ماه 1401، 36 بیمار مبتلا به کووید-19 به روش در دسترس انتخاب و به‌صورت تصادفی در سه گروه قرار گرفتند. در ادامه شدت سرفه دو ساعت پیش از انجام مداخله ثبت و سپس برای گروه گل ختمی، یک سی‌سی و برای گروه اکالیپتوس چهار سی‌سی به مدت 15 دقیقه یک بار در روز نبولایزر شد، دو ساعت پس از انجام مداخله مجددا شدت سرفه در دو گروه ثبت گردید این مداخله تا زمان بستری بیماران ادامه داشت، برای گروه کنترل مداخله‌ای انجام نشد. داده‌ها با  spss software, version 20 (spss inc., chicago, il, usa) و در سطح معناداری کمتر از 0.05 تجزیه‌و‌تحلیل شد.یافته‌ها: پیش از انجام مداخله اختلاف آماری معناداری بین سه گروه از نظر شدت سرفه وجود نداشت (0.05

comparison of the effects of althaea officinalis and eucalyptus nebulizers on the severity of cough in patients with covid-19: clinical trial

background: one of the most common and important complications of covid-19 is cough. the present study was designed with the aim of comparing the effect of althaea officinalis and eucalyptus nebulizer on the severity of cough in covid-19 patients.methods: in this randomized clinical trial, from january 2022 to june 2022, 36 patients with covid-19 were selected and randomly divided into three groups. next, the severity of cough was recorded two hours before the intervention based on the visual analogue (vas) in both groups until the patient was admitted to the hospital, then, one cc aqueous extract of althaea officinalis with five cc normal saline for the althaea officinalis group and four cc aqueous extract eucalyptus whit five cc normal saline for the eucalyptus group, were nebulized once a day for 15 minutes. two hours after the intervention, the intensity of cough was again recorded in two groups. this intervention continued until the hospitalization of the patients. no intervention was done for the control group. the data was analyzed with spss software at a significance level of less than 0.05.results: in this study before the intervention, there was no statistically significant difference between the three groups in terms of cough intensity (p>0.05), but after the intervention on the second and third days, there was a statistically significant difference between the three groups in terms of cough intensity. the rate of reduction in cough severity in althaea officinalis group was higher than the other two groups (p<0.05).  also, the results of friedman’s test indicated that althaea officinalis and eucalyptus nebulizers incense improved the severity of cough in patients over time.conclusion: the use of althaea officinalis and eucalyptus nebulizer improved the severity of cough in patients with covid-19, but althaea officinalis nebulizer had a greater effect on cough severity compared to eucalyptus. it is suggested to use althaea officinalis nebulizer as well as eucalyptus as a treatment method along with other treatment methods.