بررسی ارتباط انواع تومورهای پستان با یائسگی زنان

زمینه و هدف: با‌توجه به شیوع بالای توده‌های پستان و اهمیت غربالگری و پیگیری بدخیمی‌های آن در زنان و از آنجایی‌که دو عامل سن و تغییرات هورمونی در یائسگی در تعیین نوع پاتولوژی و پیش‌آگهی توده‌ها نقش دارند، هدف این مطالعه تعیین ارتباط میان وضعیت یائسگی و پاتولوژی توده‌ها بود.روش بررسی: این مطالعه به‌روش مقطعی تحلیلی بر روی 350 زن مبتلا به توده پستانی بدون‌سابقه بدخیمی قبلی، مراجعه‌کننده به مرکز بهداشتی–درمانی شهید بهشتی طی فروردین 1392 تا 1398 انجام شد. چک‌لیست محقق‌ساخته برای گردآوری داده‌ها از‌جمله (نوع بدخیمی، سایز توده، مکان توده، وجود یا عدم‌وجود متاستاز) مورد‌استفاده قرار گرفت. در نهایت مقایسه داده‌ها بین دو گروه یائسه و غیر‌یائسه با استفاده از spss software, version 22 (spss inc., chicago, il, usa) انجام شد.یافته‌ها: میزان شیوع بدخیمی‌ها در سنین پس‌از یائسگی و در خانم‌هایی که یائسه شده‌اند، نسبت به سنین پیش از یائسگی بیشتر بود. همچنین ارتباط معناداری بین سایز توده، وجود و یا عدم‌وجود متاستاز با یائسگی یافت شد (0.05>p)، اما بین مکان تومور با یائسگی ارتباط معناداری یافت نشد (0.05

investigating the relationship between typesof breast tumors and menopause in women

background: considering the high prevalence of breast masses and the importance of screening and follow-up for malignancies in women, and since age and hormonal changes during menopause play a role in determining the type of pathology and prognosis of the masses, the purpose of this study is to determine the relationship between menopause and mass pathology.methods: this was a cross-sectional-analytical study that was conducted in order to investigate the types of pathology of breast masses and their relationship with the age of menopause in women referred to shahid beheshti hospital in qom between april 2013 and april 2019. the inclusion criteria include: having sufficient file information and having a contact number to complete personal information, no history of cancer in other parts of the body and simultaneous malignancies, and the exclusion criteria also include: samples that were taken by cellular aspiration sampling, there were women who had a history of first-degree breast malignancy and were previously diagnosed with breast cancer and there was a possibility that the new mass under study was metastatic. finally, the patients’ information was extracted from the files and recorded in pre-prepared checklists. and the supplementary information of the incomplete files was asked and completed using the contact information of the patients. after collecting the information, using spss software version 26 and with chi-square and t-test statistical tests and considering the significance level of 0.05 the data was analyzed.results: he prevalence of malignancy in postmenopausal women was higher than in premenopausal women. also, a significant difference was found between tumor size, the presence or absence of metastasis, and menopause (p<0.05), but no significant difference was found between tumor location and menopause (p>0.05).conclusion: breast malignancies (invasive ductal carcinoma, invasive mixed carcinoma, mucinous, medullary, and papillary carcinoma) were more common in postmenopausal women than non-menopausal women. in both groups, ductal dilatation and chronic inflammation were the most benign findings, and fibroadenoma was found at a much lower rate in menopausal women than in non-menopausal.