لنفادنیت گردنی مقاوم به درمان در کودک 10 ساله: گزارش موردی

زمینه و هدف: فرد مبتلا به لنفادنیت گردنی چرکی با تظاهراتی ازجمله تب مراجعه و نیاز به درمان آنتی‌بیوتیکی دارد. در صورت عدم پاسخ به درمان می‌بایست علل دیگر از جمله موارد عفونی غیر شایع، بدخیمی و کاوازاکی را در نظر داشت. هدف این مطالعه معرفی کودکی با شک به لنفادنیت گردنی چرکی بود که در نهایت تشخیص کاوازاکی داده شد.معرفی بیمار: بیمار پسر 10 ساله که با تب و لنفادنیت شدید گردنی، به بیمارستان مرکز طبی کودکان تهران در اردیبهشت 1397 مراجعه کرد و تحت درمان آنتی‌بیوتیکی قرار گرفت. با توجه به عدم پاسخ به درمان، ادامه تب، افزایش esr  و بروز آرترالژی، برای بیمار اکوکاردیوگرافی به عمل آمد که اکتازی عروق کرونر مشاهده شد (lad>2/5 sd) و با تشخیص کاوازاکی درمان شد که به‌صورت دراماتیک به درمان پاسخ داد.نتیجه‌گیری: بیماری کاوازاکی یکی از علل لنفادنیت گردنی می‌باشد که در صورت عدم پاسخ لنفادنیت چرکی گردن به آنتی‌بیوتیک، می‌بایست مدنظر قرار گیرد.

resistant cervical lymphadenitis in a 10-year-old child: case report

background: purulent cervical lymphadenitis presents with different manifestations such as fever and erythema of the skin at the site of infection. the appropriate treatment for purulent lymphadenitis are antibiotics. if there is no response to antibiotic treatment, other causes should be considered, including uncommon infectious causes (for example mycobacterium infections or fungal infections), malignancy and kawasaki diseases, etc. this study aimed to introduce a child with suspected purulent cervical lymphadenitis, who was initially presented with purulent lymphadenitis and was treated with broad-spectrum antibiotics. due to the lack of response to treatment, further laboratory and clinical examinations were performed for him, then he was diagnosed with kawasaki disease.case presentation: a 10-year-old boy with fever and severe cervical lymphadenitis was referred to tehran children’s medical center hospital in may 2018. he had leukocytosis in his lab test and the acute reactant phase was high. he was diagnosed with purulent lymphadenitis and he was treated with broad-spectrum antibiotics. but no therapeutic response was observed, the patient’s fever continued and erythrocyte sedimentation rate (esr) increased in the laboratory tests. the patient’s knee developed arthralgia, and inflammation of the neck spread to the chest wall. therefore echocardiography was performed. the patient’s left anterior descending artery (lad) had ectasia in echocardiography (lad>2/5 sd). the patient was diagnosed with atypical kawasaki disease, therefore the appropriate treatment was started for him and a dramatic clinical response was seen. his fever stopped and the patient’s cervical lymphadenitis had completely improved. in the follow-up, the patient’s left anterior descending artery (lad) ectasia was resolved.conclusion: kawasaki disease is one of the causes of cervical lymphadenitis in children. if a patient with suspected purulent lymphadenitis is treated with appropriate antibiotics but no adequate response is seen, kawasaki disease should be considered and the patient must be re-evaluated for kawasaki disease.