بررسی فراوانی یافته‌های آندوسکوپی در بیماران مبتلا به کووید 19 مراجعه‌کننده با خونریزی گوارشی فوقانی به بیمارستان الزهرا (س) اصفهان

زمینه و هدف: خونریزی گوارشی از پیامدهای کووید-19 است که با افزایش مدت بستری و مرگ‌ومیر بیماران همراه می‌باشد. این مطالعه با هدف تعیین شیوع یافته‌های آندوسکوپی و outcome خونریزی گوارشی در بیماران مبتلا به کووید-19 بستری در بیمارستان الزهرا (س) اصفهان انجام گرفت.روش بررسی: در این مطالعه مقطعی، از بین 5800 بیمار که از شهریور تا آذر 1399 به‌علت ابتلا به کووید-19 در بیمارستان الزهرا (س) اصفهان بستری شدند، 87 بیمار که به‌علت خونریزی گوارشی فوقانی تحت آندوسکوپی قرار گرفتند، انتخاب و بررسی‌شدند. مشخصات دموگرافیک، بیماری‌های زمینه‌ای، مصرف داروهای ضدانعقاد، یافته‌های آزمایشگاهی و سرانجام بیماری برحسب یافته‌های آندوسکوپی موردبررسی و مقایسه قرار گرفت.یافته‌ها: براساس نتایج حاصله، بیماران دارای ضایعه آندوسکوپی میانگین سنی بالاتر (0/041=p)، درصد اشباع اکسیژن خون پایین‌تر (0/028=p) و شدت خونریزی بالاتری (0/018=p) داشته‌اند. فراوانی مصرف داروهای ضدانعقادی در گروه با نتیجه آندوسکوپی غیرنرمال بالاتر ولی غیرمعنادار بود. سطح هموگلوبین، پلاکت، لنفوسیت و crp در گروه آندوسکوپی نرمال و سطح nlr، ldh و دی‌دایمر در گروه غیرنرمال بالاتر بود (0/050

examining the frequency of endoscopic findings in patients with covid-19 with upper gastrointestinal bleeding referred to al-zahra hospital of isfahan

background: gastrointestinal bleeding is one of the consequences of covid-19, which is associated with increased hospitalization and patient mortality. this study was conducted to determine the prevalence of endoscopic findings and the outcome of gastrointestinal bleeding in patients with covid-19 who were hospitalized from september to december 2019 in al-zahra hospital, isfahan.methods: in this cross-sectional study, out of 5800 patients who were admitted to al-zahra hospital in isfahan from september to december 2019 due to covid-19 (according to the positive pcr test result), 87 patients who underwent endoscopy due to upper gastrointestinal bleeding by a skilled gastroenterologist, were selected and studied. demographic characteristics, underlying diseases, use of anticoagulants, and laboratory findings were studied and evaluated and finally, the disease was evaluated and compared based on endoscopic findings.results: based on the results obtained from this research, the patients with endoscopic lesions had higher average age (p=0.041), lower blood oxygen saturation percentage (p=0.028), and higher bleeding intensity (p=0.018). the frequency of using anticoagulant drugs in the group whose endoscopy results were abnormal was higher but insignificant. hemoglobin, platelet, lymphocyte, and crp levels were higher in the group whose endoscopy was normal, and nlr, ldh, and d-dimer levels were higher in the group whose endoscopy was abnormal (p<0.050). three people (11.55%) from the group with normal endoscopy and 18 people (29.5%) from the group with abnormal endoscopy died, but the frequency of death was not significantly different between the two groups (p=0.070).conclusion: the findings of the present study showed that the covid patients with upper gastrointestinal bleeding who had endoscopic lesions had significant differences in some characteristics such as age, bleeding intensity, and blood oxygen saturation percentage with patients with normal endoscopy. also, the frequency of death in patients with endoscopic lesions was relatively higher. therefore, covid patients with gastrointestinal bleeding should undergo endoscopy as soon as possible and necessary measures should be taken to control and prevent gastrointestinal bleeding.