بررسی اثر دیابت ملیتوس بر روی اکتازی عروق کرونر: گزارش کوتاه

زمینه و هدف: بیماری اکتازی عروق کرونر، دیلاتاسیون غیرطبیعی بخشی از عروق کرونر با قطر حداقل 1.5 برابر سگمان‌های مجاور است.روش بررسی: مطالعه حاضر از نوع گذشته‌نگر می‌باشد که از شهریور تا بهمن 1398 در دانشگاه علوم پزشکی کرمانشاه صورت گرفت و نتایج آن به‌صورت خلاصه گزارش شد. برای به‌دست آوردن مقالات مورد نظر جستجوی الکترونیک در پایگاه‌های داده شامل بانک‌های اطلاعاتی scopus، pubmed و sciencedirect تا مهر 1398 انجام شد. برای این جستجو از کلید واژه lrm;های coronary artery ectasia and (diabetes or diabetes mellitus ) استفاده شد.یافته‌ها: براساس استراتژی سرچ انجام شده، 106 مطالعه یافت شد که در نهایت 24 مقاله وارد تحلیل شدند و نتایج به‌دست آمده بیانگر رابطه مستقیم دیابت ملیتوس بر اکتازی عروق کرونر می‌باشد (1.51، 0.94=95%ci، 1.19=or).نتیجه‌گیری: براساس این نتایج افرادی که به دیابت ملیتوس مبتلا هستند 19% شانس بیشتری نسبت به افراد گروه کنترل برای ابتلا به اکتازی عروق کرونر دارند.

The effect of diabetes mellitus on coronary artery ectasia: brief report

Background: Coronary artery ectasia (CAE) is dilatation of an arterial segment to a diameter at least 1.5 times that of the adjacent normal coronary artery. The incidence of coronary artery ectasia is distinct in different countries that can be found in 1.2% to 5% of angiographic examinations.Methods: This is a retrospective study that was conducted from September 2019 to February 2020 in Kermanshah University of Medical Sciences and the results were reported briefly. To obtain the desired articles, electronic searches were conducted in databases including the Scopus, PubMed, and Science Direct databases without time limited until October 2019. The keywords used were Coronary Artery Ectasia AND (Diabetes OR Diabetes Mellitus ). This was done by two individuals separately and the final results were confirmed by a third person. Mixed method appraisal tool (MMAT) was used to evaluate the quality of studies. The structure of writing and the process of performing and reporting the study are based on the PRISMA checklist.Results: Based on the search strategy carried out at PubMed, Scopus and Science Direct databases, 106 studies were found, which resulted in 24 articles being analyzed based on inclusion and exclusion criteria of which three were conducted in China, 18 in Turkey and one in Sweden, Egypt, and France. Finally, 24 articles were analyzed and the results showed a direct and effective relationship between diabetes mellitus and CAE (OR=1.19, CI: 0.94, 1.51).Conclusion: Based on these results, the risk of CAE in subjects with diabetes mellitus was 19% higher than in subjects without diabetes mellitus.