Non-Compliance After First Episode of Manic or Mixed Mood State: A 17-Month Follow-up

Objective: this study aimed to evaluate the non-compliance rate in patients with bipolar i disorder (bid).methods: the patients admitted to iran psychiatric hospital who were diagnosed as a case of the firstepisode mania of bipolar i disorder (dsm-iv-tr) by 2 psychiatrists followed by one of them in a longitudinal,prospective and naturalistic study. in the follow-up early non-compliance/irregular drugs use, drugdiscontinuation and good compliance (gc) in the patients were registered in addition to the recurrences of moodepisodes. the term poor compliance (pc) was used for early non-compliance/irregular drugs use and drugdiscontinuation.results: the patients were 11 males and 11 females aged 19.6 to 59 (28.4±10.4). the study lasted 32.5months and the subjects were followed between 8 to 24 months (17±5.3). poor compliance (pc) was observed in8 subjects (38.1%) with male to female ratio of 1.7. six subjects in pc group (75%) and 3 subjects (23.1%) ingc group had a recurrence of mood episode. eight subjects with poor compliance included 3 with noncompliance/irregular use and 5 with drug discontinuation.conclusion: the poor compliance rate in bid cases admitted to this center is close to the previous studies.repetition of the study with a larger sample size and in multi-center setting is proposed.iranian journal of psychiatry and behavioral sciences (ijpbs) , volume 1, number 2, autumn and winter 2007: 46-49 .