neural imaging using single-photon avalanche diodes

Introduction: this paper analyses the ability of singlephoton avalanche diodes (spads) for neural imaging. the current trend in the production of spads moves toward the minimumdark count rate (dcr) and maximum photon detection probability (pdp). moreover, the jitter response which is the main measurement characteristic for the timing uncertainty is progressing.methods: the neural imaging process using spads can be performed by means of florescence lifetime imaging (flim), time correlated singlephoton counting (tcspc), positron emission tomography (pet), and singlephoton emission computed tomography (spect).results: this trend will result in more precise neural imaging cameras. while achieving low dcr spads is difficult in deep submicron technologies because of using higher doping profiles, higher pdps are reported in green and blue part of light. furthermore, the number of pixels integrated in the same chip is increasing with the technology progress which can result in the higher resolution of imaging.conclusion: this study proposes implemented spads in deepsubmicron technologies to be used in neural imaging cameras, due to the small size pixels and higher timing accuracies.