Early Onset Optic Neuritis Following Measles-Rubella Vaccination

Purpose: to report two cases of optic neuritis with onset less than 24 hours following measles-rubella (mr) vaccination. case report: two teenage patients developed acute optic neuritis 6 to 7 hours after mr booster vaccination. the first patient demonstrated bilateral papillitis and severe visual loss but improved significantly with pulse intravenous steroid therapy with methylprednisolone 500 mg/day. the second patient had unilateral retrobulbar optic neuritis and demonstrated excellent visual recovery without intervention. conclusion: acute optic neuritis is a rare complication of mr vaccination and may occur early after immunization.