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Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
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نویسنده
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Nassiri Nariman ,Eslani Medi ,Panahi Nekoo ,Mehravaran Shiva ,Ziaei Alireza ,Djalilian Ali R.
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منبع
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journal of ophthalmic and vision research - 2013 - دوره : 8 - شماره : 4 - صفحه:351 -358
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چکیده
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Graft versus host disease (gvhd) is a common complication of allogeneic stem cell transplantation (allo-sct). ocular gvhd develops in approximately 40–60% of patients following allo-sct and its most common clinical manifestations include keratoconjunctivitis sicca and cicatricial conjunctivitis. ocular gvhd may lead to severe ocular surface disease, which can significantly diminish quality of life and restrict daily activities. it is thus important to monitor the condition closely since with timely diagnosis, irreversible damage can be avoided. the current review will focus on updated information regarding ocular gvhd.
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کلیدواژه
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Allogeneic Stem Cell Transplantation; Bone Marrow Transplantation; Ocular Graft Versus Host Disease; Dry Eye; Keratoconjunctivitis Sicca
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آدرس
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University of California Los Angeles, David Geffen School of Medicine, Jules Stein Eye Institute, USA, University of Illinois at Chicago, Department of Ophthalmology & Visual Sciences, USA, tehran university of medical sciences tums, Farabi Eye Hospital, Eye Research Center, ایران, University of California Los Angeles, David Geffen School of Medicine, Jules Stein Eye Institute, USA, Harvard Medical School, Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, USA, University of Illinois at Chicago, Department of Ophthalmology & Visual Sciences, USA
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Authors
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