|
|
|
|
Retinal Pigment Epithelium Transplantation: Past, Present, and Future
|
|
|
|
|
|
|
|
نویسنده
|
khan ayyad zartasht ,utheim tor paaske ,eidet jon roger
|
|
منبع
|
journal of ophthalmic and vision research - 2022 - دوره : 17 - شماره : 4 - صفحه:574 -580
|
|
چکیده
|
Retinal pigment epithelium (rpe) is a monolayer of cells situated between photoreceptors and the underlying choroid. it is essential for normal retinal function. damaged rpe is associated with diseases such as age-related macular degeneration, stargardt’s macular dystrophy, and retinitis pigmentosa. rpe cells can easily be visualized in vivo, sustainable in vitro, and differentiated from stem cells with a relatively straightforward protocol. due to these properties and the clinical significance of this epithelium in various retinal diseases, rpe transplantation as a treatment modality has gained considerable interest in the last decade. this paper presents the main techniques for rpe transplantation and discusses recent clinically relevant publications.
|
|
کلیدواژه
|
Retinal Pigment Epithelium; Retinal Pigment Epithelium Transplantation; Regenerative Medicine; Vitreoretinal Surgery; Tissue Engineering.
|
|
آدرس
|
oslo university hospital, department of medical biochemistry, Norway, oslo university hospital, department of plastic and reconstructive surgery, department of ophthalmology, norway. university of oslo, faculty of dentistry, department of oral biology, Norway. sørlandet hospital arendal, department of ophthalmology, Norway. stavanger university hospital, department of ophthalmology, Norway, oslo university hospital, department of ophthalmology, Norway
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|