Pattern and Visual Prognostic Factors of Behcet’s Uveitis in Northwest Iran

Purpose: to investigate the pattern of ocular involvement in behcet’s disease (bd) with predictors of patients’ final state of vision. methods: this historical cohort encompassed the clinical records of 200 patients diagnosed according to the international criteria for bd (icbd), over a period of 17 years between 2004 and 2021. results: the prevalence of behcet’s uveitis (bu) was more common in females and patients in the fourth decade of life. ninety-five patients (47.5%) had evidence of ocular involvement in the initial ophthalmologic evaluation, and 171 patients (85.5%) manifested evidence of bu during the follow-up visits of which bilateral non-granulomatous panuveitis was the most common anatomical pattern of involvement (32.9%) followed by posterior (27.6%), anterior (26.5%), and intermediate (13.8%) uveitis. the prevalent accompanying signs were oral aphthous (67%), skin lesions (29%), and genital ulcers (19.5%). cystoid macular edema (cme) was the most frequent ocular complication (62%), followed by cataract (57.5%) and epiretinal membranes (erm) (36.5%). univariate analysis showed the following determinants: male gender, younger age at onset, panuveitis, posterior uveitis, retinal vasculitis, and longer duration of uveitis as poorer visual prognostic factors of the disease. multivariate analysis demonstrated a higher chance of poor visual prognosis of bd in patients with panuveitis, posterior uveitis, retinal vasculitis, and longer duration of uveitis. conclusion: this cohort study demonstrated an overview on epidemiological patterns of bu along with the visual prognostic factors in iranian patients.