Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity

Purpose: to investigate the association between the time of occurrence of intraocular pressure (iop) peaks during the water-drinking test (wdt) and visual field damage in a cohort of primary open-angle glaucoma (poag) patients. methods: in this retrospective, cross-sectional study, 98 eyes from 49 consecutive poag patients were followed in a referral clinical practice. the relationship between the time when iop peaks occurred during the wdt and the visual field mean deviation (md) assessed with 24-2 visual field was tested with mixed-effects models. results: md value was significantly associated with the time of iop peak occurrence (p = 0.020) when adjusting for the number of medications, but not with the iop peak values (p = 0.238). conclusion: the time of iop peaks occurrence during the wdt was associated with glaucoma severity among treated poag patients.