Photopigment Bleaching Phenomenon on Fluorescein Angiography in a Patient with Impending Central Retinal Vein Occlusion

Purpose: to present the second case of photopigment bleaching phenomenon in fluorescein angiography (fa) and the first case of this phenomenon due to impending central retinal vein occlusion (crvo). case report: a 32-year-old healthy female noticed blurred vision in her right eye one day before presentation. despite the 20/20 visual acuity at presentation, mild increased retinal vascular tortuosity and unilateral photopigment bleaching phenomenon in fa was observed in the right eye. three weeks later, she developed a complete crvo with visual acuity reduction to 20/40 that responded well to the intravitreal injection of aflibercept. conclusion: impending crvo can cause unilateral photopigment bleaching phenomenon in fa that may be due to retinal ischemia.